Colorectal cancer is a type of cancer that starts in the colon or rectum, with adenocarcinomas making up 95% of cases. Common signs and symptoms include changes in bowel habits, blood in stool, persistent abdominal discomfort, weakness or fatigue, and unexplained weight loss. Risk factors for colorectal cancer include age, family history, diet, lifestyle factors, and certain medical conditions, but it can be prevented through diet and lifestyle changes, regular screening, and medications. Early detection through screening methods like colonoscopy, fecal occult blood test, flexible sigmoidoscopy, and CT colonography is crucial for effective treatment options such as surgery, chemotherapy, radiation therapy, targeted therapy, and immunotherapy. Prognosis and survival rates vary by stage, with factors like the patient's overall health, cancer's response to treatment, and genetic factors playing a role in determining outcomes. Genetic testing and counseling are recommended for individuals with a family history of colorectal cancer to identify genetic mutations and hereditary syndromes that may increase the risk of developing the disease.